SAMEA14080409 ERS11683665 uncultured Lachnospiraceae bacterium This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run DRR014734 of study DRP001303. EBI Generic Generic.1.0 ERC000047 2023-01-03 2023-01-03 SAMEA14080409 EBI European Bioinformatics Institute 2023-01-03T00:32:55Z 2023-01-03T00:32:55Z public DRR014734_bin.25_CONCOCT_v1.1_MAG Many fragments with little to no review of assembly other than reporting of standard assembly statistics metaspadesv3.12.0 Default CONCOCT v1.1 EMG broker account, EMBL-EBI not provided 99.94 CheckM 8.94 Host-associated Mammals Digestive system not provided not provided not provided metagenome-assembled genome gut metagenome gut metagenome Polyamines (PAs), such as putrescine, Spermidine, and spermine are related with cvarious bioactivity include strong anti-inflammatory function. Increasing PA concentration in intestine using probiotics; Bifidobacterium animalis subsp. lactis LKM512 caused inhibition of senescence and enhancing longevity of mice. We found that Arg intake also showed increase PAs concentration especially Putrescine. Mouse intakes Arg and LKM 512 resulted inhibited systemic inflammation, prolonged longevity, promoted spatial learning and memory. Metagenome analysis of intestinal mictobiota in those mice showed that detection of PA synthesis-related gene were different significantly between control and test mice. SAMD00004159 DRR014734_bin.25_CONCOCT_v1.1_MAG uncultured Lachnospiraceae bacterium Illumina HiSeq 2000 multi-marker approach