<?xml version="1.0" ?>
<BioSampleSet><BioSample access="public" publication_date="2014-08-04T00:00:00.000" last_update="2019-06-20T17:03:37.344" submission_date="2014-08-04T13:04:37.733" id="2951406" accession="SAMN02951406">   <Ids>     <Id db="BioSample" is_primary="1">SAMN02951406</Id>     <Id db_label="Sample name">S.anulatus_ATCC11523</Id>   </Ids>   <Description>     <Title>Microbe sample from Streptomyces anulatus ATCC 11523</Title>     <Organism taxonomy_id="1892" taxonomy_name="Streptomyces anulatus">       <OrganismName>Streptomyces anulatus</OrganismName>     </Organism>     <Comment>       <Paragraph>Streptomycs anulatus produces the bicyclic chromopeptide actinomycin which is a potent intercalating drug with antineoplastic activities. As part of our studies of actinomycin biosynthesis, we have cloned and sequenced the actinomycin biosynthetic gene cluster in S. anulatus, previously called Streptomyces chrysomallus. In order to gain more insight in the impact of actinomycin biosynthesis in S. chrysomallus, to identify further still missing genes in the biosynthesis of the antibiotic and to evaluate the potential of that strain as a producer of other antibiotics we obtained a draft genome sequence of this strain.</Paragraph>     </Comment>   </Description>   <Owner>     <Name url="http://www.cebitec.uni-bielefeld.de/index.php/technology-platforms/genomics">Bielefeld University</Name>     <Contacts>       <Contact>         <Name>           <First>Christian</First>           <Last>Ruckert</Last>         </Name>       </Contact>     </Contacts>   </Owner>   <Models>     <Model>Microbe, viral or environmental</Model>   </Models>   <Package display_name="Microbe; version 1.0">Microbe.1.0</Package>   <Attributes>     <Attribute attribute_name="strain" harmonized_name="strain" display_name="strain">ATCC 11523</Attribute>     <Attribute attribute_name="collection_date" harmonized_name="collection_date" display_name="collection date">unknown</Attribute>     <Attribute attribute_name="geo_loc_name" harmonized_name="geo_loc_name" display_name="geographic location">missing</Attribute>     <Attribute attribute_name="isolation_source" harmonized_name="isolation_source" display_name="isolation source">unknown</Attribute>     <Attribute attribute_name="biomaterial_provider" harmonized_name="biomaterial_provider" display_name="biomaterial provider">ATCC 11523</Attribute>     <Attribute attribute_name="culture_collection" harmonized_name="culture_collection" display_name="culture collection">ATCC:11523</Attribute>     <Attribute attribute_name="sample_type" harmonized_name="sample_type" display_name="sample type">missing</Attribute>     <Attribute attribute_name="type-material">type strain of Streptomyces chrysomallus</Attribute>   </Attributes>   <Links>     <Link type="entrez" target="bioproject" label="PRJNA257397">257397</Link>   </Links>   <Status when="2014-08-04T13:04:37.733" status="live"/> </BioSample> </BioSampleSet>
